Research of the Department of Molecular Genetics focuses on viroid research, functional genomics of hop, antisensing and gene silencing,
anti-tumoric plant nucleases, and virus variability.
Viroid research
- Focused on PSTVd and hop viroids
- Study on biochemical aspects of viroid-caused pathogenesis, propagation, antisensing and variability
- Analysis of adaptability, evolution and variability under stress conditions
- Induction and mechanisms of paralyzing effects caused by viroids
- Transfer of viroid populations to weed species and probing viroid elimination processes
Functional genomics of hop
- Genomic and expression libraries focused on genes co-determining lupulin production
- Isolation and characterization hop transcription factors and their complexes
- Analysis of transcrition factors network determining biosynthesis of medicinal prenylchalcones
Anti-tumorogenic plant nuclease
- Molecular genetic analysis of plant nuclease I and its homologues as a source for for medicinal experiments, analysis of anticancer action
- Clonning and comparative functional genomics and proteomics of plant nucleases and nuclease biogenesis
- Recombinant plant nucleases preparation, structure analysis and modifications